Here is a list of objectives and references:
Learning objectives for the meeting:
By the end of the presentation, listeners will:
- Understand what deep brain stimulation is and how the system is implanted
- Be able to identify which patients with Parkinson’s Disease are appropriate for DBS
- Understand the role of OT in treating patients who have DBS or who may be eligible for DBS
- Learn how Adaptive DBS can help patients with PD regain more “on-time” with good symptom control
- Understand expectations for DBS from a therapy perspective
Current references that are relevant to the presentation/meeting:
- Stanslaski, S., Summers, R.L.S., Tonder, L. et al. Sensing data and methodology from the Adaptive DBS Algorithm for Personalized Therapy in Parkinson’s Disease (ADAPT-PD) clinical trial. npj Parkinsons Dis. 10, 174 (2024). https://doi.org/10.1038/s41531-024-00772-5. Licensed under CC BY 4.0: https://creativecommons.org/licenses/by/4.0/
- Jimenez-Shahed J. Device profile of the percept PC deep brain stimulation system for the treatment of Parkinson’s disease and related disorders. Expert Rev Med Devices. 2021 Apr;18(4):319-332.
- Thenaisie Y, Palmisano C, Canessa A, et al. Towards adaptive deep brain stimulation: clinical and technical notes on a novel commercial device for chronic brain sensing. J Neural Eng. 2021 Aug 31;18(4).
- Yin Z, Zhu G, Zhao B, et al. Local field potentials in Parkinson's disease: A frequency-based review. Neurobiology of Disease. 2021;155:105372’
- Morelli N, Summers RLS. Association of subthalamic beta frequency sub-bands to symptom severity in patients with Parkinson's disease: A systematic review. Parkinsonism & Related Disorders. 2023;110.
- Van Wijk BCM, de Bie RMA, Beudel M. A systematic review of local field potential physiomarkers in Parkinson’s disease: from clinical correlations to adaptive deep brain stimulation algorithms. Journal of Neurology. 2023;270(2):1162-1177.
- Darcy N, Lofredi R, Al-Fatly B, et al. Spectral and spatial distribution of subthalamic beta peak activity in Parkinson's disease patients. Experimental Neurology. 2022:114150.
- Hvingelby, V., Khalil, F., Massey, F., Hoyningen, A., San Xu, S., Candelario-McKeown, J., ... & Krüger, M. T. (2025). Directional deep brain stimulation electrodes in Parkinson’s disease: meta-analysis and systematic review of the literature. Journal of Neurology, Neurosurgery & Psychiatry, 96(2), 188-198
